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3. A strong base; a substance that liberates hydroxyl ions (OH-) when in solution.

4. The entrance of a substance into the body through a break in the skin.

6. The raised areas, or wheals, that occur on the skin, associated with vasodilation due to histamine release. Commonly called “hives”.

7. A chemical substance that liberates hydrogen (H+) when in solution.

9. The entrance of a substance into the body through the respiratory tract.

11. The entrance of a substance into the body directly through the skin (_________ Absorption).

13. Medical and biological science that studies the detection, chemistry, pharmacological actions, and antidotes of toxic substances.

15. An immunoglobulin molecule that interacts with an antigen to facilitate its removal.

17. Information center staffed by trained personnel that provides up-to-date toxicologic information (_______ Control Center).

18. A hypersensitive state acquired through exposure to a particular antigen. Synonymous with Hypersensitivity.

19. Alternative term for antibody.

20. A substance capable of inducing an allergy of specific hypersensitivity. May be protein based (most common) or non-protein based.


1. Product of mast cells and basophiles that cause vasodilation, increased capillary permeability, bronchoconstriction, and contraction of the gut (principal chemical mediator of allergic reactions).

2. A susbtance that neutralizes a poison or the effects of a poison.

3. Any substance, under appropriate conditions, that is capable of inducing a specific immune response (most are proteins).

5. Process of releasing histamine and other substances stored in granule form.

8. The entrance of a substance into the body through the gastrointestinal tract.

10. An unusual or exaggerated allergic reaction to a foreign protein or other substance.

12. Second-line agent (drug type) used in the treatment of anaphylaxis (only given after initial epinephrine dose).

14. A hypersensitive state, or allergy, with a genetic predisposition.

16. A dose of a drug in excess of that usually prescribed.


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